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Fluphenazine dihydrochloride

Name: Fluphenazine dihydrochloride
Brand: TargetMol
SKU: T0068
Price: 43 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0068Cas No. 146-56-5

Alias Prolixin, Fluphenazine hydrochloride

Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metabolic process of this commonly used dopamine antagonist.

Fluphenazine dihydrochloride

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Purity: 99.23%

Catalog No. T0068Alias Prolixin, Fluphenazine hydrochlorideCas No. 146-56-5

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$43	In Stock	In Stock
100 mg	$52	In Stock	In Stock
200 mg	$75	In Stock	In Stock
500 mg	$119	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.23%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS HPLC

Product Introduction

Bioactivity

Description	Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metabolic process of this commonly used dopamine antagonist.
Synonyms	Prolixin, Fluphenazine hydrochloride

Chemical Properties

Molecular Weight	510.44
Formula	C₂₂H₂₈Cl₂F₃N₃OS
Cas No.	146-56-5
Smiles	Cl.Cl.OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1
Relative Density.	no data available

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (489.77 mM), Sonication is recommended.

Ethanol: 28 mg/mL (54.85 mM), Sonication is recommended.

H2O: 92 mg/mL (180.24 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.92 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9591 mL	9.7955 mL	19.5909 mL	97.9547 mL
5 mM	0.3918 mL	1.9591 mL	3.9182 mL	19.5909 mL
10 mM	0.1959 mL	0.9795 mL	1.9591 mL	9.7955 mL
20 mM	0.0980 mL	0.4898 mL	0.9795 mL	4.8977 mL
50 mM	0.0392 mL	0.1959 mL	0.3918 mL	1.9591 mL

H2O/DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0196 mL	0.0980 mL	0.1959 mL	0.9795 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc